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R. Sean Norman , M.Sc., Ph.D.
Associate Professor
Director, Molecular Microbial Ecology Lab
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University of South Carolina
Department of Environmental Health Sciences
921 Assembly Street
Columbia, SC 29208

Phone: (803) 777-0940
Fax: (803) 777-3391
E-mail: rsnorman@mailbox.sc.edu

BIOGRAPHICAL INFORMATION
2007: Assistant Professor, Dept. of Environmental Health Sciences, University of South Carolina
2007: Interim Director, USC Environmental Genomics Core Facility, University of South Carolina
2006-2007: Research Assistant Professor, Dept. of Environmental Health Sciences, University of South Carolina.
2005: Adjunct Instructor, Rutgers University, New Brunswick, NJ.
2004-2006: Postdoctoral Research Associate, Biotechnology Center for Agriculture and the Environment, Rutgers University, New Brunswick, NJ.
1999-2003: Graduate Research Assistant, Marine Biomedicine and Environmental Sciences Center, Medical University of South Carolina, Charleston, SC.
1996-1999: Graduate Research Assistant, Dept. Microbiology and Immunology, Environmental Studies, University of Charleston, Charleston, SC.


Honors & Awards:
2002: MUSC Student Research Day 1st place Ph.D. oral presentation
2001: Slocum-Luntz Foundation grant for studies related to understanding mechanisms of manipulating hydrocarbon-degrading microbial communities
1999: Outstanding Graduate Student Award- Masters in Environmental Studies
RESEARCH
Dr. Norman's Molecular Microbial Ecology Laboratory research foci are:
  1. Examining how bacteria communicate and coordinate gene expression by exploring the diversity of genes involved in bacterial cell density dependent gene regulation and how these processes affect microbial community functional diversity in numerous ecosystems.
  2. Exploring the potential of using novel nanotechnology-based therapeutics as an alternative to traditional antibiotic treatment of infectious bacterial infections.
  3. Understanding how a rapidly expanding urban landscape is affecting the structure and function of microbial communities found throughout South Carolina watersheds. Because urbanization ultimately results in increased runoff of pollutants into the environment, we are examining the genetic capability of bacteria to degrade numerous priority pollutants as well as understanding how these emerging pollutants may be affecting the distribution of bacterial pathogens in the environment.
  4. Using state-of-the-art DNA sequencing technologies to explore the metagenomes of marine stromatolites and hypersaline microbial mats.
SELECTED PUBLICATIONS

Norman, R.S. , J.W. Stone, A. Gole, C.J. Murphy, and T.L. Sabo-Attwood. 2007. Targeted photothermal lysis of the pathogenic bacteria, Pseudomonas aeruginosa using gold nanorods. Nano Letters, In Prep.

Norman, R.S. , B. Bey, P. Visscher, A.W. Decho. 2007. A functional genomic approach to understanding quorum sensing in the SRB, Desulfovibrio sp. In Prep.

Norman, R.S. , P. Visscher, A.W. Decho. 2007. Sequencing the draft genome of the SRB, Desulfovibrio sp. H2.3JLac. In prep.

Chadhain, S.M., R.S. Norman, K.V. Pesce, J.J. Kukor, and G.J. Zylstra. 2006. Microbial dioxygenase gene population shifts during polycyclic aromatic hydrocarbon biodegradation. (co-first author) Applied and Environmental Microbiology, 72:4078-4087.

Norman, R.S. , P. Moeller, T.J. McDonald, and P.J. Morris. 2004. Effect of pyocyanin on a crude oil-degrading microbial community. Applied and Environmental Microbiology, 70: 4004-4011.

Norman, R.S. 2003. The effect of Pseudomonas aeruginosa on the functional diversity of a crude oil-degrading microbial community. Doctoral Dissertation.

Norman, R.S. , R. Frontera-Suau, and P.J. Morris. 2002. Variability in Pseudomonas aeruginosa lipopolysaccharide expression during crude oil degradation. Applied and Environmental Microbiology, 68: 5096-5103. .

Norman, R.S. 1999. Molecular determination of the microbial community structure associated with the dechlorination of 2,3,4,5-tetrachlorobiphenyl. Masters Thesis.

Columbia, SC 29208 • 803-777-7000 • enhsweb@mailbox.sc.edu