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RESEARCH
Research Focus

The Aphasia Laboratory is located in the Department of Communication Sciences and Disorders at the University of South Carolina and is directed by Julius Fridriksson, Ph.D. The research foci of the lab include: 1) Understanding the neurophysiology of aphasia recovery in stroke; 2) Understanding speech motor perception in normal and disordered populations (e.g. autism, stroke, etc.); 3) Understanding the neural basis of motor speech processing.  Much of this research relies on technologies such as MRI (including DTI, fMRI, VBM, LSM) and transcranial magnetic stimulation (TMS). 


Download Stroke Research Brochure (PDF)

Research Funding

Our research is funded by the following grants to Julius Fridriksson:

Current NIH Funding:

Principal investigator, “National Institute of Deafness and other Communication Disorders.” Neurological Predictors of Anomia Recovery in Aphasia, (R01 DC008355. Funding period 4/1/2007-3/31/2012. Annual budget: $225,000/year). This project investigates the relationship between cortical integrity and outcome of anomia treatment in patients with aphasia.

Principal investigator, “National Institute of Deafness and other Communication Disorders.” A Unified Neuroanatomical Model of Speech Perception and Production: Implications (R01 DC009571. Funding period 4/1/2009-3/31/2014. Requested funding: $250,000/year). This project will examine the neural mechanism supporting speech perception and production. Special emphasis will be placed on translating basic research findings into treatment of apraxia of speech and conduction aphasia. Joint PI: Chris Rorden.

Co-investigator, “National Institute on Neurological Disorders and Stroke.” Dissociating Components of the Attentional Network in Neglect (R01 NS054266 funding period: 8/1/2006-7/31/2011: $205,000/year). The purpose of this grant is to investigate brain damage associated with neglect in stroke patients. PI: Chris Rorden

Completed funding:

Principal investigator, “National Institute of Deafness and other Communication Disorders.” Neurological Predictors of Aphasia Recovery (R03 DC005915 funding period: 8/1/03-7/31/07; total funding: $225,000). The purpose of this study was to investigate the relationship among cerebral perfusion, lesion size, aphasia, and left hemi-spatial neglect in early stroke.

Co-PI, “Anonymous donor.” Brain atrophy and normal aging. (Funding period: 2006-2009; total funding: $100,000). The purpose of this research is to examine the relationship between white and gray matter atrophy in the normally aging brain and cognition. Co-PI: Leonardo Bonilha

Co-investigator, “National Institute on Aging.” Processing Discourse Reference in Mind and Brain, (R21 AG030445. Funding period: 5/1/2008-4/30/2010. Annual budget: $150,000). This research aims to uncover the functional and neural processes that underlie reference comprehension, especially with respect to the relation between reference form and referent salience. PI: Amit Almor
 

 

Research Collaborators

University of South Carolina:  Amit Almor, Ph.D.; Stacy Fritz, Ph.D. (Lab Website); Roger Newman-Norlund, Ph.D.; Chris Rorden, Ph.D. ; John Henderson, Ph.D.; Souvik Sen, M.D.,MPH.; Dirk B. den Ouden, Ph.D.; Fernanda Ferreira, Ph.D.,

Medical University of South Carolina: Leonardo Bonilha, M.D., Ph.D.; Ali Tabesh, Ph.D.; Joseph Helpern, Ph.D.

City University of New York: Marom Bikson, Ph.D.; Abhishek Datta, M.S.E.E.; Lucas Parra, Ph.D.

University of Nottingham: Paul S. Morgan, Ph.D.

University of Iceland: Sigridur Magnusdottir, Ph.D.; Haukur Hjaltason, M.D.

University of Arizona: Audrey Holland, Ph.D.
 

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