The Spatial Epidemiology Group Some members of this group are Andrew Lawson (Professor) Monir Hossain (postdoctoral fellow) Hae-Ryoung Song (postdoctoral fellow) Ji-in Kim (postdoctoral fellow) Research Interests My research interests mainly focus on the development of statistical methods in spatial and environmental epidemiology. I also have interests in disease surveillance, health data mining and space -time problems, directional statistics and environmetrics. I have also worked in geoscience applications and in some areas relating to stochastic geometry. My main technical interests lie in Bayesian methodology for spatial problems and in the development of real time simulation-based methods for optimal surveillance. I am a WHO advisor in Disease Mapping and Risk Assessment, and have a wide range of publications in this area, including 5 books. Slides from the CDC Cancer Conference (2003) course: Introduction to Bayesian Mapping Methods Downloadable Datasets: Data sets from the book: Lawson, A. B. (2001) Statistical Methods in Spatial Epidemiology. Wiley, New York, can be downloaded here in Zip format Mixture Model WinBugs code: Download from here the WinBugs code for a two component relative risk mixture model in the class considered in Lawson and Clark (2002) Statistics in Medicine 21,359-370 Fortran and R code for a range of Disease Mapping Models R/SPlus code find the program code for a selection of disease mapping models: here here find the program code for the Scottish lip cancer example Fortran code here find Fortran90 code for a range of simple mapping models: BYM here Marshall here Gamma-Poisson (EB) here MLwiN macros from the book Disease Mapping with WinBUGS and MLwiN Macros used in this book relate to version 2.0 of MLwiN. Here find the downloadable macros WinBUGS ODC files from the book Disease Mapping with WinBUGS and MLwiN are available: chapters 7 here chapter 8 here chapter 9 here Corrected tables in chapter 8 for low birth weight example: here Please note that due to confidentiality requirements no dataset is downloadable for the Weibull spatial analysis in chapter 9. chapters 4 6 and 8: ODCs here, data (chapter 6 ) here data (chapter 8) here WinBUGS ODC files and R code from the book Statistical Methods in Spatial Epidemiology 2nd ed are available: Appendix R code WinBUGS code WinBUGS ODC files and R code from the book Bayesian Disease Mapping: hierarchical modeling in spatial epidemiology
Comment: are exceedence probabilities useful for detecting hot spots?
Books Details of a number of books written or edited by Dr Lawson (and co-authors) appear below
Courses Courses given by invitation:
including 1/2 day WinBUGS extension University of Aberdeen , UK (2 day course) 1999, 2000, 2001, 2002, 2003 University of Edinburgh, UK (3 day course) 2004 University of Gothenburg, Sweden (4 day course) 2000, 2001 Ministry of Health, Wellington, New Zealand (4 day course) 2001 KU Leuven, Belgium (2 day course) 2000 University of Western Australia (3 day course) 2005 New South Wales Health and the Australian Social Science Network, Sydney, Australia (2 day course) 2005
CDC cancer Conference, Atlanta (one day) 2003
ASA JSM Toronto 2004 (one day course)
GISVET international conference (2 day course) 2007
My Publications List (i) Books and Chapters Published: Lawson, A. B. (1989) Statistical Analysis of a direction-dependent planar point process. Applied Surface Modelling , chapter 16, (eds Creasie and Craggs), Ellis Horwood Lawson, A.B. Waller, L. and Biggeri, A.(1995) chief editor of a special issue ‘Spatial Disease Patterns’ of Statistics in Medicine, volume 14, 21/22, November 1995 Lawson, A. B. (1997) Statistical Maps, pp10 in “Encyclopedia of Biostatistics” eds: Armitage,P. and Colton,T.,volume 14, Wiley, New York Lawson, A. B. (1997) Some Spatial Statistical Tools for Pattern Recognition. in (eds Stein, A. Penning de Vries, F. and J. Schut) Quantitative Approaches in Systems Analysis, 12, pp 10, AB-DLO Wageningen. Lawson, A. B. Biggeri, A. Boehning, D. Lesaffre, E. Viel, J-F and Bertollini, R. (1999) Disease Mapping and Risk Assessment for Public Health. Wiley, New York Lawson, A.B. and Clark, A. MCMC methods for putative sources of Hazard and General Clustering chapter 9, in Lawson , A. B. et al (1999) Disease Mapping and Risk Assessment for Public Health. Wiley, New York Lawson, A. B., Biggeri, A. and Dreassi, E. Edge Effects in disease Mapping chapter 6, in Lawson , A. B. et al (1999) Disease Mapping and Risk Assessment for Public Health. Wiley, New York Lawson, A. B. and Kulldorff, M. A review of Cluster detection Methods chapter 7, in Lawson , A. B. et al (1999) Disease Mapping and Risk Assessment for Public Health. Wiley, New York Lawson, A. B., Biggeri, A. and Williams, F.L.R. A Review of Modelling Approaches in Health Risk Assessment around Putative Sources chapter 17, in Lawson , A. B. et al (1999) Disease Mapping and Risk Assessment for Public Health. Wiley, New York Biggeri, A., Divino, F., Frigessi, A., Lawson, A., Boehning, D. Lesaffre, E. and Viel, J-F. Introduction to Spatial Models in Ecological Analysis. chapter 13, in Lawson , A. B. et al (1999)Disease Mapping and Risk Assessment for Public Health. Wiley, New York Schlattmann, P., Boehning, D. Clark, A. and Lawson, A. B. Lung Cancer Mortality in Women in Germany 1995- A Case Study in Disease Mapping. chapter 31, in Lawson , A. B. et al (1999) Disease Mapping and Risk Assessment for Public Health. Wiley, New York Lawson, A. B. and Clark, A. B.(1999) Markov Chain Monte Carlo methods for clustering for case event and count data in spatial epidemiology.in Statistics and Epidemiology: Environement and Clinical Trials (ed M. E Halloran and D. Berry) Springer verlag **invited chapter** Lawson, A. B. and Cressie, N.A. C.(2000) Spatial Statistical Methods for Environmental Epidemiology. Handbook of Statistics (Bio-Environmental and Public Health Statistics), volume 17, (eds. Rao, C. R. and P. K. Sen) ** invited chapter Lawson, A. B. (2000) Population Health Surveillance. in The Encyclopedia of Environmetrics eds El-Shaarawi, A. and Piegorsch, W. Wiley, New York Lawson, A. B.(2001) Statistical Methods in Spatial Epidemiology Wiley, New York Lawson, A. B. and Williams, F. L. R. (2001) An Introductory Guide to Disease Mapping. Wiley Medical Sciences, New York. Lawson, A. B. and Denison, D. (2002) (eds) Spatial Cluster Modelling Chapman & Hall CRC, London. Lawson, A. and Clark, A. (2002) Spatio-temporal cluster modelling of small area health data in Lawson and Denison (eds)(2002) Spatial Cluster Modelling, Chapman & Hall CRC, London. Lawson, A. and Denison, D. (2002) Spatial Cluster Modelling: an Overview in Lawson and Denison (eds.) (2002) Spatial Cluster Modelling, Chapman & Hall CRC, London. Lawson, A. (2002)Statistical Methods for Risk Assessment Around Putative Point Sources in The Encyclopedia of Life Support Systems. UNESCO. ed Zimmerman, D, El-Shaarawi, A. Lawson, A. B. Browne, W. J. and Vidal Rodeiro, C. L. (2003) Disease Mapping with WinBUGS and MLwiN. Wiley London Lawson, A. (2003) Issues in the Space-Time analysis of Public Health Surveillance Data in Monitoring the Health of Populations: Statistical Methods for Public Health Surveillance. eds Brookmeyer, R. and Stroup, D. Oxford University Press. Lawson, A. B. (2003) Statistics in Spatial Epidemiology, entry in Encyclopedia of Statistical Sciences 2nd ed Balakrishnan, N. , Reid, C. B. and B. Vidakovic (eds), Wiley, New York Lawson, A. B. and Kleinman, K. (2005) Spatial and Syndromic Surveillance for Public Health, Wiley, New York Lawson, A. B. (2006) Statistical Methods for Spatial epidemiology 2nd Ed Wiley, New York Lawson, A. B. (2008) Bayesian Disease Mapping: Hierarchical Modeling in Spatial Epidemiology CRC Press Boca Raton (ii) Refereed Journal Papers Published: Bevan, K. , McDonald, A. and Lawson, A. (1979) A landslide in Bilsdale, North York Moors. Earth Surface Processes, 3,4, 407 Lawson, A. B. (1983) Rank analysis of covariance : alternative approaches. The Statistician, 32, 331-337. Lawson, A. B. (1988) On tests for spatial trend in a non-homogeneous Poisson process. Journal of Applied Statistics (special issue in circular data),15, 2, 225-234. Lawson, A. B. (1988) Fitting the von Mises distribution on GLIM Journal of Applied Statistics (special issue in circular data),15, 2, 255-260. Lloyd, O., Lloyd, M. Williams, F. L. R. and Lawson, A. B. (1988) Twinning in human populations and in cattle exposed to air pollution from incinerators.British Journal of Industrial Medicine, 45, 556-560. Lawson, A. B. (1992) GLIM and normalising constant models in spatial and directional data analysis. Computational Statistics and Data Analysis, 13, 331-348. Williams, F. L. R. , Lawson, A. B. and Lloyd, O. (1992) Low sex ratios of births in areas at risk from incinerators, as shown by geographical analysis and 3-dimensional mapping. International Journal of Epidemiology, 21, 2, 311-319. Lawson, A. B. (1993) A deviance residual for heterogeneous spatial Poisson processes. Biometrics, 49, 3, 889-897. Lawson, A. B. (1993) On the analysis of mortality events around a prespecified fixed point. Journal of the Royal Statistical Society, A, 156, 2, 363-377. Lawson, A. B. (1993) On composite intensity score tests. Communications in Statistics (theory and methods), 22, 11, 3223-3235. Lawson, A. B. and Williams, F. L. R. (1993) Applications of extraction mapping in environmental epidemiology. Statistics in Medicine, 12, 1249-1258. Lawson, A B and Williams, F L R (1994) Armadale: a case study in Environmental Epidemiology. Jour. Royal Stat. Soc.,A, 157,2,285-298 Lawson, A B (1994) Using Spatial Gaussian priors to model heterogeneity in Environmental Epidemiology. Proc. Practical Bayesian Statistics Conference, Nottingham, The Statistician, 43,1,69-76. Waller, L and Lawson, A.B.(1995) The Power of Tests of focussed disease clustering. Statistics in Medicine,14,2291-2308. Lawson, A.B. and Viel, J-F.(1995) Tests for directional space-time interaction in epidemiological data. Statistics in Medicine,14,2383-2392. Lawson, A.B (1995) McMC methods for putative pollution source problems in environmental epidemiology Statistics in Medicine, 14, 2473-2486. Lawson,A.B. and Waller,L.(1996) A Review of Point Pattern Methods for Spatial Modelling of Events around Sources of Pollution.Environmetrics, 7, 471-488. Lawson,A.B. and Harrington,N.W.(1996) The analysis of putative environmental pollution gradients in spatially correlated epidemiological data. to appear in ‘Statistics and The Environment’, Advances in Applied Statistics ed J.N.Jeffers (Jour of Appl Stat,23,301-310) Lawson, A. B. (1997) An angular-radial dependence model for point process data. Communications in Statistics (theory and methods), 26, 1, 237–245. Lawson, A. B. and Clark, A B. (1999) Small area cluster modelling via RJMcMC methods Journal of the National Institute of Public Health, 48(2), **special invited issue**, 113-120. Lawson, A. B. (2000) Cluster Modelling of Disease Incidence via RJMcMC: a comparative evaluation.Statistics in Medicine,19,17/18,2361-2376 Lawson, A. B. and Leimich, P.(2000) Approaches to space-time modelling of infectious disease behaviour. IMA Journal of Mathematics Applied in Medicine and Biology, 17, 1-13. Lawson, A. B. and Williams, F. L. R. (2000) Spatial competing risk modelling with applications in spatial epidemiology. Statistics in Medicine,19,17/18,2451-2468 Lawson, A. B. Biggeri, A. Boehning, D. et al.(2000) Disease Mapping Models: an empirical evaluation Statistics in Medicine,19,17/18,2217-2242 Cressie, N. A. C. and Lawson, A. B. (2000) Hierarchical Probability Models and Bayesian Analysis of Minefield locations Advances in Applied Probability, 32, 2, 315-330. Stevenson, M., Wilesmith, J., Ryan, J., Morris, R., Lawson, A., Pfeiffer, D., Lin, D. (2000) A descriptive spatial analysis of the BSE epidemic in Great Britain. Veterinary Record, 147, 379-384 Lawson, A. B. (2001) Disease Map Reconstruction: an Introductory Tutorial. ** invited Biostatistics tutorial Statistics in Medicine, 20,2183-2204 Lawson, A. and Clark, A. (2002) Spatial Mixture Relative Risk Models applied to Disease Mapping Statistics in Medicine, 21,359-370 Lawson, A. B., S. Simeon, M. Kulldorff, A. Biggeri and C. Magnani (2005) Small area cluster modelling: a comparison of object models with flexible forms. submitted Lawson, A. B. (2002) Bayesian augmentation methods for estimation of missing infectives in spatial infectious disease modelling. Stevenson, M., Morris, R., Lawson, A., Wilesmith, J. W., Ryan, J. B. M., Jackson, R. (2002) Spatial aspects of the BSE epidemic in Great Britain: a Bayesian ecological analysis. Clark*, A. B. and Lawson, A. B. (2004) An Evaluation of non-parametric relative risk estimators for disease maps Computational Statistics and Data Analysis 47, 63-78 Vidal Rodeiro*, C. and Lawson, A. B. (2005) An evaluation of Edge Effects in Disease Mapping Computational Statistics and Data Analysis 49(1), 45-62 Lawson, A. B, A. B. Clark and C. L. Vidal-Rodeiro (2004) Developments in General and Syndromic Surveillance for Small Area Health Data, Journal of Applied Statistics (special issue) 31, 951-966. Lawson, A. B. and Zhou, H. (2005) Spatial Statistical Modeling of Disease Outbreaks: with particular reference to the UK FMD epidemic of 2001. Preventive Veterinary Medicine (to appear) Durr, P., Tait, N. and Lawson, A. B. (2005) Bayesian Hierarchical Modelling to enhance the epidemiological value of abattoir surveys for bovine fasciolosis. Preventive Veterinary Medicine (to appear) Hossain, M. and Lawson, A. B. (2005) Local Likelihood Disease Clustering : Development and Evaluation Environmental and Ecological Statistics 12,3,259-273 Greco, F. Lawson, A. B.,Cocchi, D. Temples, T. (2005) Voronoi Tesselation and other methods for misaligned small area health data Environmental and Ecological Statistics 12,379-395 Stevenson, M., Morris, R., Lawson, A., Wilesmith, J. W., Ryan, J. B. M., Jackson, R. (2005) Area level risks for BSE in British Cattle before and after the July 1988 meat and bone meal feed ban Preventive Veterinary Medicine 69, 129-144. Pickle, L. Waller, L and Lawson, A. B. (2005) Current Practices in cancer spatial data analysis: a call for guidance International Journal of Health Geographics. 4:3 1-5 Lawson, A. B. (2006) Disease Cluster Detection: A critique and a Bayesian Proposal, Statistics in Medicine, 25,897-916 Vidal Rodeiro, C. and Lawson, A. B. (2006) Online updating of space-time Disease-Surveillance models via Particle Filters Statistical Methods in Medical Research 15,1-22 Clark, A. B. and Lawson, A. B. (2006) Surveillance of Individual level disease Maps Statistical Methods in Medical Research 15.1-15 (iii) Other Journal Papers (since 1989) Published: Lawson, A. B. (1989) read contribution to Cancer Near Nuclear Installations. Journal of the Royal Statistical Society, A, 152, 3, 374-375. Lawson, A. B. (1992) read contribution to Geyer and Thomson ‘Constrained Monte Carlo Maximum Likelihood for dependent data’. Journal of the Royal Statistical Society, B, 54, 3 Lawson, A. B. (1993) read contribution to the meeting on the Gibbs Sampler. Journal of the Royal Statistical Society, B, 55, 1, 61-62. Lawson, A. B. (1993) on ‘A bivariate Cramer-von Mises type of test for spatial randomness’ Journal of the Royal Statistical Society, C, (Applied Statistics), 42, 1, 43-54. Lawson, A. B. (1994) read contribution to Grenander and Miller ‘Representation of knowledge in complex systems’. Journal of the Royal Statistical Society, B, 56, 594-595. Lawson, A. B. (1996) Use of deprivation indices in small area studies. Journal of Epidemiology and Community Health, 50, 689. Lawson, A. B. (1996) on Auto-Poisson models for small area health data by J. Ferrrandiz Biometrics Lawson, A. B. (1996) on A population-weighted Moran I statsitsic by N. Oden Statistics in Medicine Lawson, A. B. (1998) invited commentary (seconding the vote of thanks) on Diggle, P. Tawn, J. and Moyeed, R. ‘Model-based Geostatistics’ read paper: Journal of the Royal Statistical Society, C, 47,299-350 Lawson, A. B. (1999) Medical atlas mapping and classification (**invited commentary**) for the The Lancet Lawson , A. B. (2001) invited discussion of papers by Kulldorff, Knorr-Held and Best, Rogerson, and McNeil et al Journal Royal Statistical Society A,164, 100-102 Lawson, A. B. and Clark, A. (2002) read contribution to Spiegelhalter, D., Best, N., Carlin, B. and van der Linde, A. Bayesian Measures of Model Complexity and Fit. Journal of the Royal Statitscal Society B, 64, 3, 1-34 Lawson, A. B, (2006) read contribution to Baddeley et al Residuals for Point Processes JRSS B (to appear) Lawson, A. B. and W. Piegorsch (2006) read contribution to Lee and Nelder Generalised Hierarchical linear Models JRSS C (to appear)
(iv) Conference Papers (since 2000) Published: Lawson, A. (2000) Bayesian augmentation methods for estimation of missing infectives in spatial infectious disease modelling. invited paper ASA JSM Indianapolis Lawson, A. and Clark, A. (2001) Spatial Mixture Relative Risk Models in Disease Mapping. Contributed Paper ASA JSM Atlanta August 2001 Lawson, A. B. and Kulldorff, M. (2001) Small area cluster modelling via point and line object dependencies. (ISBA Eurostat proceedings) JI Macdiarmid, JAS Ross, S Watt, L Osman, A Lawson, D Godden, R. Stephenson. Potential long term effects of diving at work. Do professional divers have medical complaints? Annual Scientific Meeting of the Association of NHS Occupational Physicians 2001 Lawson, A. (2001) Data Mining and Surveillance of Disease Maps Health and GIS Sheffield Conference Lawson, A. and Clark, A. (2001) Spatial Mixture Relative Risk Models in Disease Mapping. Health and GIS Sheffield Conference Lawson, A. B. (2004) FMD small area data surveillance and Modeling GISVET International conference, Guelph, Ontario (Plenary speaker) Lawson, A. B. and Vidal Rodeiro, C. (2005) Spatial Surveillance of Small Area Disease Events: Particle Filtering Methods GEOMED meeting Cambridge (2005)
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